Medical Researches
Likely Ineffective
Based on 16 Researches
We explored the effects of magnesium treatment in a unique case involving a 62-year-old woman with stage IV colon cancer undergoing oxaliplatin therapy. Shortly after her first infusion, we observed that she experienced significant neurological symptoms, including right hemibody paresthesia, muscle cramping in her right calf, and dysphonia.
To address these symptoms, she was administered intravenous magnesium sulfate along with calcium gluconate. Remarkably, within three hours, all her symptoms resolved. While this case suggests that magnesium can provide relief from cramps and other neurological side effects, it is important to note that magnesium was used in conjunction with other medications, making it challenging to assess its isolated effectiveness.
For future doses, the oxaliplatin was adjusted by reducing the dose and extending the infusion duration, which minimized her symptoms to occasional mild paresthesia. In summary, while magnesium showed promise in this case, further research is needed to determine its specific impact on leg cramps in a clearer, more controlled manner.
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Magnesium oxide treats leg crampsA randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
High relevance for magnesium use
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
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We sought to understand the effectiveness of oral magnesium in treating leg cramps experienced by pregnant women. Our study was well-structured, involving a double-blind, randomized, placebo-controlled design. It included 86 healthy pregnant women between 14 to 34 weeks of gestation who encountered leg cramps at least twice a week, and we followed them over a four-week period.
At the end of the study, we discovered that the women taking magnesium bisglycinate chelate (300 mg per day) reported a significant reduction in cramp frequency—86% experienced at least a 50% drop compared to only 60.5% of those taking the placebo. Additionally, those on magnesium also noted a notable decrease in cramp intensity, with 69.8% achieving a similar improvement versus just 48.8% in the placebo group.
Encouragingly, we found no major side effects reported in either group, such as nausea or diarrhea. Our findings suggest that magnesium supplements can effectively reduce both the frequency and severity of leg cramps during pregnancy, offering a potential treatment option for women dealing with this common issue.
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Magnesium's potential against crampsRandomised, cross-over, placebo controlled trial of magnesium citrate in the treatment of chronic persistent leg cramps.
Directly investigates magnesium's impact
We set out to investigate whether magnesium citrate could be an effective remedy for those who experience bothersome leg cramps, particularly at night. In our study, we used a randomised, double-blind, cross-over, placebo-controlled design to ensure reliable results. Participants suffering from regular leg cramps were recruited and given either magnesium citrate or a matching placebo over six weeks.
Our findings revealed that those who began the trial with the placebo experienced an average reduction in cramps when taking magnesium, with a median of 5 cramps compared to 9 on the placebo. Moreover, a notable percentage of participants felt that the magnesium treatment had indeed helped them, with 78% reporting benefits, as opposed to 54% who felt the placebo was effective.
While these results suggest that magnesium may have a positive impact, it’s essential to mention that the impact on cramp severity and duration wasn’t significantly different between the two groups. Additionally, some participants did report experiencing diarrhoea as a side effect of magnesium. Overall, we believe magnesium shows promise in alleviating nocturnal leg cramps and recommend further research to fully evaluate its effectiveness.
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We explored the effectiveness of magnesium treatment for leg cramps during pregnancy through a review of five randomized trials involving 352 women.
The trials varied in quality, but interestingly, they included comparisons of different treatments such as calcium and sodium chloride against placebos. While the placebo-controlled trial that investigated calcium did not show any significant benefits, there were hints of promise for magnesium.
For those looking for relief from troublesome leg cramps, our analysis indicated that magnesium—specifically in the forms of magnesium lactate or citrate—might help. Taking 5mmol in the morning and 10mmol in the evening seemed to provide the best results.
However, the evidence remains mixed, and we couldn't pinpoint any strong benefits from other combinations or supplements tested. So, while magnesium might be beneficial, it’s essential to approach it as one option among many.
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User Reviews
Good
Based on 246 Reviews
Quality sleep improvement
I’ve been considering this magnesium product for quite some time. I liked the composition and dosage. After one week of use, I noticed improvements in my sleep quality; no more leg cramps, and my muscles feel relaxed. The tablets are a bit large, but overall, it’s a beneficial mineral, and I'm happy to continue using it until I finish the two packs I ordered.
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This chelated magnesium has worked wonders! I paired it with vitamin B6 to enhance its effects. After increasing my magnesium intake per my doctor's advice, I've noticed a significant reduction in headaches and leg cramps. When taking vitamin D, I've learned the importance of also taking chelated magnesium, and I would certainly recommend this combination.
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Magnesium has a calming effect on my muscles. Since I started taking it, my night-time foot cramps have stopped entirely. However, I must be cautious with the dosage to prevent any digestive issues, especially diarrhoea. I take two capsules daily without any negative effects.
This quality magnesium is as per my doctor's advice. After taking it, my muscle condition improved, cramps have vanished, and I now enjoy more restful and sound sleep. It’s important to take care of yourself!
You can sleep soundly! I purchased it after a recommendation from an acupuncture and moxibustion practitioner for my leg cramps at night, which previously disrupted my sleep. To be honest, I was sceptical about the supplement, but since I started taking it, all those issues have resolved. I’m delighted that I can sleep through the night peacefully! I will continue to use it.
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